The San Diego region has one of the highest concentrations of high-tech companies in the United States, and the third highest concentration of biotech companies in the nation. A little known fact is that 93% of San Diego businesses are small and have less than 20 employees. This allows for flexibility and innovation. Small businesses need support from strategic industry associations to assist companies with a variety of issues. Some of the programs or agencies listed below were jump-started by the City, and the City works closely with all of the organizations.